Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 17/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544246 | 0.76 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL18542847 | 0.75 | NR3C2 (0.34) | KCNH2 | |
| SCHEMBL20679486 | 0.75 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL20679441 | 0.74 | KCNH2 (0.53) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL20679263 | 0.74 | KCNH2 (0.53) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL20679510 | 0.74 | KCNH2 (0.49) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL18544254 | 0.74 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL20679241 | 0.74 | KCNH2 (0.66) | KCNH2 | |
| SCHEMBL20679511 | 0.74 | KCNH2 (0.56) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL18542787 | 0.74 | KCNH2 (0.58) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029602-A2 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-02-23 | — | — | WO | disclosed |