Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20679297 | 0.78 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL20679429 | 0.76 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL18544466 | 0.76 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL20679254 | 0.76 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL20679469 | 0.76 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL18529137 | 0.76 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL20679509 | 0.76 | MTNR1A (0.43) | KCNH2 | |
| SCHEMBL18529139 | 0.76 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL18543789 | 0.75 | PDE3B (0.34) | KCNH2MAOAMAOB | |
| SCHEMBL20679421 | 0.75 | KCNH2 (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029602-A2 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-02-23 | — | — | WO | disclosed |