Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849612 | 0.89 | GPR52 (0.48) | GPR52PRKDCTP53POLBHPGD | |
| SCHEMBL1850159 | 0.85 | GPR52 (0.54) | GPR52PRKDCTP53POLBHPGD | |
| SCHEMBL3219547 | 0.83 | GPR52 (0.54) | GPR52TP53POLBHPGDS1PR4 | |
| SCHEMBL1850789 | 0.82 | GPR52 (0.53) | GPR52PRKDCTP53POLBHPGD | |
| SCHEMBL1848922 | 0.82 | GPR52 (0.46) | GPR52PRKDCTP53POLBHPGD | |
| SCHEMBL3196519 | 0.81 | GPR52 (0.47) | GPR52PRKDCTP53POLBHPGD | |
| SCHEMBL3204381 | 0.81 | GPR52 (0.49) | GPR52PRKDCTP53POLBHPGD | |
| SCHEMBL1848571 | 0.81 | GPR52 (0.52) | GPR52TP53POLBHPGDS1PR4 | |
| SCHEMBL1848119 | 0.81 | GPR52 (0.71) | GPR52HPGDS1PR4S1PR5ALDH1A1 | |
| SCHEMBL1847859 | 0.81 | GPR52 (0.46) | GPR52PRKDCTP53POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |