SCHEMBL1854664

SCHEMBL1854664

CCCCCCCCCCCC(N)=NO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.52
SPHK1 Q9NYA1 2/20 0.52
SPHK2 Q9NRA0 1/20 0.52
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
FAAH O00519 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
SOAT1 P35610 1/20 0.43
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 6/20 0.42
PPARD Q03181 6/20 0.42
PPARA Q07869 6/20 0.42
HDAC11 Q96DB2 5/20 0.42
TSHR P16473 4/20 0.42
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12127825 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL6387164 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL1855781 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL15174081 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL15174509 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL1341663 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL5773009 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL15174483 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL22854103 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A
SCHEMBL2405667 1.00 CYP2D6 (0.52) CYP2D6SPHK1SPHK2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617762-B2 Carboxy derivatives with antiinflamatory properties SITRYX THERAPEUTICS LIMITED (GB) 2026-05-05 US disclosed
EP-4081511-B3 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2026-03-04 EP disclosed
EP-4442319-A2 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2024-10-09 EP disclosed
EP-4081511-B1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2024-07-31 EP disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed
EP-4081511-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2022-11-02 EP disclosed
WO-2021130492-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2021-07-01 WO disclosed
EP-1470102-B1 SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) MERCK SERONO SA (CH) 2011-05-25 EP disclosed
US-7592477-B2 Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (PTPs) LABORATOIRES SERONO SA (CH) 2009-09-22 US disclosed
US-20050124656-A1 Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases(ptps) APPLIED RESEARCH SYSTEMS ARS (NL) 2005-06-09 US disclosed
EP-1470102-A1 SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) Applied Research Systems ARS Holding N.V. (AN) 2004-10-27 EP disclosed
WO-2003064376-A1 SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2003-08-07 WO disclosed
EP-0204217-B1 RECOVERY OF METALS ADSORBED ON CHELATING AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-09-13 EP disclosed
EP-0171704-B1 METHOD FOR ELUTING A METAL ADSORBED ON A CHELATING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-05-10 EP disclosed
US-4797264-A ELUTION OF METALS BY TREATMENT WITH BASIC SOLUTIONS OF REDUCING AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-01-10 US disclosed
US-4786481-A INORGANIC SULFIDE, HYDROXIDE AND AMINE SOLUTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-22 US disclosed
EP-0204217-A1 Recovery of metals adsorbed on chelating agents SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-10 EP disclosed
EP-0171704-A1 Method for eluting a metal adsorbed on a chelating agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 CYP2D6 2114/4885SPHK1 3875/4885SPHK2 3631/4885
US-20050124656-A1 Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases(ptps) PTPRS, PTPA, PTPMT1 CYP2D6 3053/4885SPHK1 2279/4885SPHK2 2550/4885
US-12617762-B2 Carboxy derivatives with antiinflamatory properties CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 CYP2D6 860/4885SPHK1 2540/4885SPHK2 2714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.