CPA2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL14509143	0.46	7/20
SCHEMBL6824349	0.58	6/20
SCHEMBL6827926	0.58	6/20
SCHEMBL6827930	0.58	6/20
SCHEMBL6824195	0.57	6/20
SCHEMBL14542979	0.57	6/20
SCHEMBL7162400	0.45	6/20
SCHEMBL1642187	0.38	6/20
SCHEMBL7391699	0.64	5/20
SCHEMBL2632703	0.61	5/20
SCHEMBL2632695	0.62	4/20
SCHEMBL9697346	0.58	4/20
SCHEMBL8271877	0.51	4/20
SCHEMBL7497156	0.48	4/20
SCHEMBL7497160	0.48	4/20
SCHEMBL11228295	0.48	4/20
SCHEMBL10718337	0.47	4/20
SCHEMBL10716135	0.46	4/20
SCHEMBL7048091	0.43	4/20
SCHEMBL7047064	0.42	4/20

Clinical trials — most relevant to CPA2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Fluticasone and Salmeterol in Allergic Rhinitis	PHASE4	COMPLETED
Comparative Clinical Study to Evaluate the Possible Efficacy and Safety of Oral N-Acetyl Cysteine Versus Rectal Diclofenac in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis	PHASE1/PHASE2	COMPLETED
Study of the Mechanisms of Asthma	PHASE1	COMPLETED
Chemokine Mechanisms in Chronic Pelvic Pain	nan	COMPLETED
Markers in Acute Pancreatitis-1	nan	COMPLETED
Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3	nan	COMPLETED
Disorders of the Acute Phase Response Following Trauma and Invasive Surgery	nan	ENROLLING_BY_INVITATION
Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients	nan	UNKNOWN
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations	nan	COMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED
Acute Pancreatitis Targets (APT) Study	nan	COMPLETED
Kinetics of Nasal Cytokine Responses to Mechanical Stimulation	nan	COMPLETED
Genomic Research in Alpha-1 Antitrypsin Deficiency	nan	COMPLETED
Screening for Prognostic Biomarkers of Severe Bell's Palsy in Adults	nan	RECRUITING
Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests	nan	UNKNOWN
A Longitudinal Study to Analyse the Correlation Between CAI and Bilirubin	nan	UNKNOWN
Ovarian Reserve and Matrix Metalloproteinases	nan	COMPLETED
In Vivo Assessment of Histamine Pharmacodynamics	nan	WITHDRAWN
Allergy and Immunology Natural History Study	nan	RECRUITING
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study	nan	RECRUITING
Genetic Determinism of Epithelial Barrier Defects in Irritable Bowel Syndrome	nan	WITHDRAWN
Respiratory Cathepsins, Proteases Inhibitors and Glycosaminoglycans (GAG) in Mucopolysaccharidosis	nan	COMPLETED
Use of Blood Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma (HCC)	nan	UNKNOWN
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma	nan	ACTIVE_NOT_RECRUITING
Assessing the Impacts of a UESAD on Laryngeal Symptoms and Salivary Pepsin	nan	COMPLETED
Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors	nan	RECRUITING
Proteases in Patients With Prostate Cancer That Has Spread to the Bone	nan	COMPLETED
The Canadian Multicentre CSF Monitoring and Biomarker Study	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a CPA2 binder may also engage these)

Protein	Name	Similarity
P09954	—	1.000	P09954 →
Q504N0	—	0.996	Q504N0 →
P00732	—	0.994	P00732 →
CPB1	Carboxypeptidase B	0.993	landscape →
D4D675	—	0.993	D4D675 →
O02350	—	0.993	O02350 →
P00731	—	0.993	P00731 →
P19223	—	0.993	P19223 →
P09955	—	0.993	P09955 →
P00730	—	0.993	P00730 →
P19222	—	0.992	P19222 →
Q8WXQ8	—	0.992	Q8WXQ8 →
Q9VL86	—	0.991	Q9VL86 →
A0A1S4F020	—	0.991	A0A1S4F020 →
Q9JHH6	—	0.991	Q9JHH6 →
B8JLQ9	—	0.990	B8JLQ9 →
CPA1	Carboxypeptidase A1	0.990	landscape →
Q3T905	—	0.990	Q3T905 →
Q0II73	—	0.990	Q0II73 →
CPA4	Carboxypeptidase A4	0.989	landscape →
Q6P8K8	—	0.989	Q6P8K8 →
P55261	—	0.988	P55261 →
Q7TPZ8	—	0.988	Q7TPZ8 →
D4B5N0	—	0.987	D4B5N0 →
B6V865	—	0.987	B6V865 →
Q9EQV9	—	0.987	Q9EQV9 →
Q8R4H4	—	0.985	Q8R4H4 →
Q4R7R2	—	0.985	Q4R7R2 →
D4DL57	—	0.985	D4DL57 →
Q29NC4	—	0.985	Q29NC4 →