SCHEMBL185471

SCHEMBL185471

NCC(C(=O)O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.72
TSHR P16473 1/20 0.72
ALDH1A1 P00352 5/20 0.49
CTSD P07339 1/20 0.45
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
GRM8 O00222 1/20 0.41
GRM4 Q14833 1/20 0.41
MAPK1 P28482 2/20 0.41
CA1 P00915 1/20 0.40
CASP7 P55210 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29475159 1.00 CYP1A2 (0.72) CYP1A2TSHRALDH1A1CTSDMAPT
SCHEMBL9479735 0.85 CYP1A2 (0.74) CYP1A2TSHRALDH1A1CTSDMAPT
SCHEMBL7263695 0.84 CYP1A2 (1.00) CYP1A2TSHRALDH1A1CTSDMAPT
SCHEMBL7263686 0.84 CYP1A2 (1.00) CYP1A2TSHRALDH1A1CTSDMAPT
SCHEMBL475205 0.84 CYP1A2 (0.72) CYP1A2TSHRALDH1A1CTSDMEN1
SCHEMBL475201 0.84 CYP1A2 (0.72) CYP1A2TSHRALDH1A1CTSDMEN1
SCHEMBL4726276 0.81 CYP1A2 (0.68) CYP1A2TSHRALDH1A1MEN1KMT2A
SCHEMBL9710218 0.81 CYP1A2 (0.73) CYP1A2TSHRALDH1A1CTSDMAPT
SCHEMBL9710227 0.81 CYP1A2 (0.73) CYP1A2TSHRALDH1A1CTSDMAPT
SCHEMBL4726270 0.81 CYP1A2 (0.68) CYP1A2TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023657-B2 Reversible protein multimers, methods for their production and use LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) 2018-07-17 US claimed
US-20260146089-A1 ANTIBODIES TARGETING CD3 AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2026-05-28 US disclosed
US-12612456-B2 CD19 antibodies and methods of using the same MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-04-28 US disclosed
US-20260078340-A1 SCAFFOLDS WITH STABILIZED MHC MOLECULES FOR IMMUNE-CELL MANIPULATION UNIV DANMARKS TEKNISKE (DK) 2026-03-19 US disclosed
US-20260042860-A1 ANTI-CD24 ANTIBODIES AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-02-12 US disclosed
EP-4680647-A2 ANTIBODIES TARGETING CD3 AND USES THEREOF Memorial Sloan-Kettering Cancer Center (US) 2026-01-21 EP disclosed
US-20260015435-A1 ANTI-POLYSIALIC ACID ANTIBODIES AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-01-15 US disclosed
US-12509515-B2 CD22 antibodies and methods of using the same MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-12-30 US disclosed
US-12497592-B2 Scaffolds with stabilized MHC molecules for immune-cell manipulation DANMARKS TEKNISKE UNIVERSITET (DK) 2025-12-16 US disclosed
US-12486323-B2 Anti-L1-CAM antibodies and uses thereof MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2025-12-02 US disclosed
EP-1038031-A1 MASS SPECTROMETRIC METHODS FOR SEQUENCING NUCLEIC ACIDS SEQUENOM, INC. (US) 2000-09-27 EP disclosed
EP-1010008-A2 MASS SPECTROMETRIC DETECTION OF POLYPEPTIDES SEQUENOM, INC. (US) 2000-06-21 EP disclosed
WO-1999057318-A2 INFRARED MATRIX-ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRIC ANALYSIS OF MACROMOLECULES SEQUENOM, INC. (US) 1999-11-11 WO disclosed
EP-0937096-A2 HIGH DENSITY IMMOBILIZATION OF NUCLEIC ACIDS SEQUENOM, INC. (US) 1999-08-25 EP disclosed
EP-0937097-A1 COMPOSITIONS AND METHODS FOR IMMOBILIZING NUCLEIC ACIDS TO SOLID SUPPORTS SEQUENOM, INC. (US) 1999-08-25 EP disclosed
WO-1999031278-A1 MASS SPECTROMETRIC METHODS FOR SEQUENCING NUCLEIC ACIDS SEQUENOM, INC. (US) 1999-06-24 WO disclosed
US-5900481-A Bead linkers for immobilizing nucleic acids to solid supports SEQUENOM, INC. (US) 1999-05-04 US disclosed
WO-1999012040-A2 MASS SPECTROMETRIC DETECTION OF POLYPEPTIDES SEQUENOM, INC. (US) 1999-03-11 WO disclosed
WO-1998020019-A1 COMPOSITIONS AND METHODS FOR IMMOBILIZING NUCLEIC ACIDS TO SOLID SUPPORTS SEQUENOM, INC. (US) 1998-05-14 WO disclosed
WO-1998020020-A2 HIGH DENSITY IMMOBILIZATION OF NUCLEIC ACIDS SEQUENOM, INC. (US) 1998-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078340-A1 SCAFFOLDS WITH STABILIZED MHC MOLECULES FOR IMMUNE-CELL MANIPULATION IL2, MICA, HLA-C CYP1A2 4527/4885TSHR 3153/4885ALDH1A1 3755/4885
US-20260042860-A1 ANTI-CD24 ANTIBODIES AND USES THEREOF CD22, FCGR2A, CD2BP2 CYP1A2 4256/4885TSHR 2912/4885ALDH1A1 793/4885
US-12612456-B2 CD19 antibodies and methods of using the same CD74, CD4, CD2 CYP1A2 4409/4885TSHR 1127/4885ALDH1A1 4081/4885
US-20260015435-A1 ANTI-POLYSIALIC ACID ANTIBODIES AND USES THEREOF VSIG8, CD74, FCGR2A CYP1A2 4596/4885TSHR 2180/4885ALDH1A1 4437/4885
US-20260146089-A1 ANTIBODIES TARGETING CD3 AND USES THEREOF IGLV6-57, IGSF11, VSIG8 CYP1A2 4508/4885TSHR 398/4885ALDH1A1 4368/4885
US-12509515-B2 CD22 antibodies and methods of using the same CD74, CD22, CD2 CYP1A2 3194/4885TSHR 1597/4885ALDH1A1 3646/4885
US-10023657-B2 Reversible protein multimers, methods for their production and use CD4, CD74, CD69 CYP1A2 4864/4885TSHR 423/4885ALDH1A1 4582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.