Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20324201 | 0.88 | ACACB (0.39) | ACACB | |
| SCHEMBL24920843 | 0.85 | ACACB (0.33) | ACACBKCNH2 | |
| SCHEMBL18611812 | 0.83 | ACACB (0.41) | ACACB | |
| SCHEMBL22047351 | 0.83 | ACACB (0.41) | ACACB | |
| SCHEMBL18611814 | 0.83 | ACACB (0.41) | ACACB | |
| SCHEMBL18551220 | 0.81 | ACACB (0.34) | ACACBALDH1A1 | |
| SCHEMBL19604932 | 0.76 | ACACB (0.38) | ACACB | |
| SCHEMBL26748742 | 0.76 | ACACB (0.38) | ACACB | |
| SCHEMBL19604991 | 0.75 | ACACB (0.41) | ACACB | |
| SCHEMBL18591766 | 0.73 | ACACB (0.33) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017030814-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINS | Arvinas, Inc. (US) | 2017-02-23 | — | — | WO | disclosed |