Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18591766 | 0.89 | ACACB (0.33) | ACACBHTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL26328562 | 0.89 | ACACB (0.33) | ACACBHTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL20325131 | 0.87 | GRM5 (0.35) | ACACBHTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL20324201 | 0.86 | ACACB (0.39) | ACACB | |
| SCHEMBL18551213 | 0.85 | ACACB (0.34) | ACACBKCNH2 | |
| SCHEMBL18612041 | 0.85 | HTR2A (0.33) | HTR2AHTR2CHTR2BSIGMAR1DRD2 | |
| SCHEMBL25059246 | 0.82 | ACACB (0.34) | ACACB | |
| SCHEMBL18611814 | 0.81 | ACACB (0.41) | ACACB | |
| SCHEMBL18611812 | 0.81 | ACACB (0.41) | ACACB | |
| SCHEMBL22047351 | 0.81 | ACACB (0.41) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |