Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | GRK6 | P43250 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17213070 | 0.92 | GRK6 (0.52) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL17213103 | 0.90 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL18540634 | 0.89 | TYMP (0.42) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL18552318 | 0.85 | FFAR4 (0.41) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL18552365 | 0.85 | DHODH (0.40) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL17213036 | 0.85 | GRK6 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL18552403 | 0.84 | FGFR1 (0.42) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL18552337 | 0.83 | CTSA (0.38) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL18552348 | 0.83 | MEN1 (0.39) | ALDH1A1KDM4EHSD17B10HPGDTYMP | |
| SCHEMBL18552262 | 0.82 | MAPT (0.44) | ALDH1A1KDM4EHSD17B10HPGDTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050939-A1 | SMALL MOLECULE INHIBITORS OF G PROTEIN COUPLED RECEPTOR 6 KINASE POLYPEPTIDES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050939-A1 | SMALL MOLECULE INHIBITORS OF G PROTEIN COUPLED RECEPTOR 6 KINASE POLYPEPTIDES | GRK6, GRK2, GRK3 | ALDH1A1 4745/4885KDM4E 4539/4885HSD17B10 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.