Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71401 | 0.94 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL31301140 | 0.94 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL71402 | 0.94 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL5379059 | 0.94 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL2627847 | 0.94 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL20437737 | 0.93 | PTPN1 (0.64) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL4255766 | 0.91 | PTPN1 (0.71) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL4255769 | 0.91 | PTPN1 (0.71) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL16687964 | 0.89 | PTPN1 (0.68) | PTPN1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL4733209 | 0.88 | NPC1 (0.63) | PTPN1ALDH1A1MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793495-B2 | Synthesis of polyaryl substituted aryl compounds | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2020-10-06 | — | — | US | disclosed |
| US-20180215687-A1 | SYNTHESIS OF ARYL COMPOUNDS | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2018-08-02 | — | — | US | disclosed |
| WO-2017027933-A1 | SYNTHESIS OF ARYL COMPOUNDS | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793495-B2 | Synthesis of polyaryl substituted aryl compounds | UTS2R, UBTF, UGT1A1 | PTPN1 1763/4885ALDH1A1 521/4885MAPT 2569/4885 |
| US-20180215687-A1 | SYNTHESIS OF ARYL COMPOUNDS | UTS2R, UGT1A1, NAT1 | PTPN1 1427/4885ALDH1A1 145/4885MAPT 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.