SCHEMBL71401

SCHEMBL71401

COC(=O)c1ccc(/C=C/c2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.73
ALDH1A1 P00352 2/20 0.73
MAPT P10636 7/20 0.64
LMNA P02545 3/20 0.64
NPC1 O15118 2/20 0.64
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
TDP1 Q9NUW8 1/20 0.61
CA12 O43570 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
CA14 Q9ULX7 1/20 0.61
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
ATM Q13315 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
TSHR P16473 1/20 0.58
MAOB P27338 1/20 0.57
HTT P42858 1/20 0.55
RAB9A P51151 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5379059 1.00 PTPN1 (0.73) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL2627847 1.00 PTPN1 (0.73) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL71402 1.00 PTPN1 (0.73) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL31301140 1.00 PTPN1 (0.73) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL18552317 0.94 PTPN1 (0.72) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL23332277 0.92 TDP1 (0.77) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL19909724 0.92 TDP1 (0.77) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL12294526 0.92 TDP1 (0.77) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL2615886 0.92 PTPN1 (0.65) PTPN1ALDH1A1MAPTLMNANPC1
SCHEMBL14789231 0.92 ALDH1A1 (0.89) PTPN1ALDH1A1MAPTLMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0813516-B1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS EASTMAN CHEM CO (US) 1999-12-01 EP claimed
EP-0813516-A1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS EASTMAN CHEMICAL COMPANY (US) 1997-12-29 EP claimed
WO-1996027578-A1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS EASTMAN CHEMICAL COMPANY (US) 1996-09-12 WO claimed
US-5473098-A Process for the preparation of stilbenedicarboxylate esters EASTMAN CHEMICAL COMPANY (US) 1995-12-05 US claimed
WO-1993022366-A1 WATER-DISPERSIBLE COPOLYMER CONTAINING UVA AND UVB LIGHT-ABSORBING MONOMERS UNILEVER PLC (GB) 1993-11-11 WO claimed
US-5243021-A Polylactam, polyester, polyether copolymers containing stilbene groups LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-09-07 US claimed
EP-2414350-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2014-11-12 EP disclosed
US-8796466-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2014-08-05 US disclosed
US-8765029-B2 Light transmissive articles and methods thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-07-01 US disclosed
EP-2619195-A1 HEPATITIS C VIRUS INHIBITORS Bristol-Myers Squibb Company (US) 2013-07-31 EP disclosed
US-8440769-B2 Polyester stilbene composition SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-05-14 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-4551520-A Polyesters of trans-4,4-stilbenedicarboxylic acid, terephthalic acid and 1,4-cyclohexanedimethanol EASTMAN KODAK COMPANY (US) 1985-11-05 US disclosed
US-4468510-A FILMS, FIBERS, MOLDING PLASTICS, LOW GAS PERMEABILITY EASTMAN KODAK COMPANY (US) 1984-08-28 US disclosed
US-4459402-A Copolyesters comprising repeating units from trans-4,4'-stilbenedicarboxylic acid, terephthalic acid and/or 2,6-naphthalenedicarboxylic acid, and 1,4-butanediol EASTMAN KODAK COMPANY (US) 1984-07-10 US disclosed
US-4420607-A FILMS FIBERS, MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed
US-4414382-A Copolyesters derived from 2,6-naphthalenedicarboxylic acid, trans-4,4'-stilbenedicarboxylic acid and ethylene glycol EASTMAN KODAK COMPANY (US) 1983-11-08 US disclosed
US-4073777-A Radiation crosslinkable polyester and polyesteramide compositions containing sulfonate groups in the form of a metallic salt and unsaturated groups EASTMAN KODAK COMPANY (US) 1978-02-14 US disclosed
US-3953498-A Diesters and diacids of phenanthrene GULF RESEARCH & DEVELOPMENT COMPANY (US) 1976-04-27 US disclosed