Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306602 | 0.84 | TNF (0.38) | TNFALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL7320513 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7312705 | 0.83 | TNF (0.39) | TNFALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL7313345 | 0.83 | ALDH1A1 (0.48) | TNFALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL10958150 | 0.81 | MEN1 (0.46) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7315249 | 0.80 | TNF (0.39) | TNFALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL7313402 | 0.80 | TNF (0.39) | TNFALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL7310260 | 0.80 | TNF (0.39) | TNFALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL4314516 | 0.80 | MEN1 (0.43) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7319321 | 0.79 | MAPT (0.49) | TNFALDH1A1MAPTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3337795-A1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | Femtogenix Limited (GB) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017032983-A1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | FEMTOGENIX LIMITED (GB) | 2017-03-02 | — | — | WO | disclosed |