SCHEMBL18554369

SCHEMBL18554369

CC(C)(C)N1C[C@H](F)C[C@H]1C(=O)NCc1cccc(Cl)c1F

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CFD P00746 17/20 0.58
P2RX7 Q99572 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25542676 0.85 CFD (0.68) CFD
SCHEMBL12480916 0.84 CFD (0.60) CFD
SCHEMBL17024945 0.84 CFD (0.60) CFD
SCHEMBL17023353 0.84 CFD (0.60) CFD
SCHEMBL19458590 0.84 CFD (0.60) CFD
SCHEMBL17023343 0.83 CFD (0.64) CFD
SCHEMBL19216059 0.81 CFD (0.68) CFD
SCHEMBL12481283 0.81 CFD (0.57) CFDP2RX7
SCHEMBL18649373 0.79 CFD (0.60) CFD
SCHEMBL17056169 0.78 CFD (0.63) CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017035355-A1 ETHER COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS ACHILLION PHARMACEUTICALS, INC. (US) 2017-03-02 WO disclosed