Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 19/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554385 | 1.00 | CFD (0.49) | CFDCYP2C9 | |
| SCHEMBL18578247 | 0.84 | CFD (0.64) | CFDCYP2C9 | |
| SCHEMBL18554430 | 0.76 | EPHX2 (0.43) | CFDCYP2C9 | |
| SCHEMBL18554429 | 0.76 | EPHX2 (0.43) | CFDCYP2C9 | |
| SCHEMBL29177412 | 0.76 | GAA (0.44) | CFDCYP2C9 | |
| Hydrochloric Acid SCHEMBL20378179 | 0.75 | EPHX2 (0.43) | CFDCYP2C9 | |
| Hydrochloric Acid SCHEMBL20378176 | 0.75 | EPHX2 (0.43) | CFDCYP2C9 | |
| SCHEMBL19233854 | 0.74 | CFD (0.44) | CFDCYP2C9 | |
| SCHEMBL29841056 | 0.73 | CFD (0.60) | CFDCYP2C9 | |
| SCHEMBL28710431 | 0.73 | CFD (0.60) | CFDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3340982-A1 | COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017035408-A1 | COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |