Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554656 | 1.00 | KMT2A (0.53) | KMT2ACASP3PTPN1TLR2MDM4 | |
| SCHEMBL17790570 | 0.90 | KMT2A (0.56) | KMT2ACASP3PTPN1TLR2MDM4 | |
| SCHEMBL18554660 | 0.89 | CASP3 (0.58) | KMT2ACASP3MDM4TP53MDM2 | |
| SCHEMBL18554664 | 0.89 | CASP3 (0.58) | KMT2ACASP3MDM4TP53MDM2 | |
| SCHEMBL17826082 | 0.87 | KMT2A (0.56) | KMT2ACASP3PTPN1TLR2MDM4 | |
| SCHEMBL29400679 | 0.87 | KMT2A (0.56) | KMT2ACASP3PTPN1TLR2MDM4 | |
| SCHEMBL13658468 | 0.87 | KMT2A (0.56) | KMT2ACASP3PTPN1TLR2MDM4 | |
| SCHEMBL12928621 | 0.87 | KMT2A (0.56) | KMT2ACASP3PTPN1TLR2MDM4 | |
| SCHEMBL14997839 | 0.87 | KMT2A (0.58) | KMT2ACASP3PTPN1TLR2MDM4 | |
| SCHEMBL20504185 | 0.87 | KMT2A (0.58) | KMT2ACASP3PTPN1TLR2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ACADEMIA SINICA (TW) | 2021-01-12 | — | — | US | disclosed |
| US-20180244713-A1 | SIALYLTRANSFERASE INHIBITORS AND USES THEREOF | ACADEMIA SINICA (TW) | 2018-08-30 | — | — | US | disclosed |
| EP-3341387-A1 | SIALYLTRANSFERASE INHIBITORS AND USES THEREOF | Academia Sinica (TW) | 2018-07-04 | — | — | EP | disclosed |
| CN-108026138-A | Sialyltransferase inhibitors and uses thereof | 中央研究院 | 2018-05-11 | — | — | CN | disclosed |
| WO-2017035501-A1 | SIALYLTRANSFERASE INHIBITORS AND USES THEREOF | ACADEMIA SINICA (TW) | 2017-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ST6GAL1, NEU1, GALNT1 | KMT2A 1743/4885CASP3 4384/4885PTPN1 1475/4885 |
| US-20180244713-A1 | SIALYLTRANSFERASE INHIBITORS AND USES THEREOF | ST6GAL1, NEU1, GALNT1 | KMT2A 1743/4885CASP3 4384/4885PTPN1 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.