Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647414 | 0.76 | EP300 (0.44) | EPHX1SMN1; SMN2ZDHHC20ZDHHC2LMNA | |
| SCHEMBL3208116 | 0.76 | POLB (0.41) | SMN1; SMN2POLBCYP3A4KDM4EHPGD | |
| SCHEMBL19573442 | 0.76 | EP300 (0.44) | EPHX1SMN1; SMN2ZDHHC20ZDHHC2LMNA | |
| SCHEMBL15913628 | 0.76 | ZDHHC7 (0.43) | ZDHHC7EPHX1SMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL540777 | 0.75 | TSHR (0.39) | SMN1; SMN2ZDHHC20ZDHHC2MAPTPOLB | |
| SCHEMBL3248973 | 0.74 | EP300 (0.42) | EPHX1SMN1; SMN2ZDHHC20ZDHHC2LMNA | |
| SCHEMBL3248980 | 0.74 | EP300 (0.42) | EPHX1SMN1; SMN2ZDHHC20ZDHHC2LMNA | |
| SCHEMBL23252449 | 0.74 | ADORA2A (0.40) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL20205749 | 0.74 | CYP2C9 (0.48) | ZDHHC7SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL19830184 | 0.73 | LMNA (0.39) | SMN1; SMN2ZDHHC20ZDHHC2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580392-B2 | HIV replication inhibiting pyrimidines | JANSSEN PHARMACEUTICA NV (BE) | 2017-02-28 | — | — | US | disclosed |