Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24404522 | 1.00 | ADRB2 (0.65) | ADRB2CHRM3 | |
| SCHEMBL18557793 | 0.97 | ADRB2 (0.63) | ADRB2CHRM3 | |
| SCHEMBL24404519 | 0.95 | ADRB2 (0.63) | ADRB2CHRM3 | |
| SCHEMBL18557665 | 0.95 | ADRB2 (0.63) | ADRB2CHRM3 | |
| SCHEMBL24404511 | 0.95 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL18557618 | 0.95 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL24404512 | 0.95 | ADRB2 (0.66) | ADRB2CHRM3 | |
| SCHEMBL18557795 | 0.95 | ADRB2 (0.66) | ADRB2CHRM3 | |
| SCHEMBL24404429 | 0.94 | ADRB2 (0.69) | ADRB2CHRM3 | |
| SCHEMBL24404507 | 0.93 | ADRB2 (0.59) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579314-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-02-28 | — | — | US | disclosed |