Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19362711 | 0.93 | RAB9A (0.53) | NPY5RCYP2D6RAB9ANPC1MAPT | |
| SCHEMBL18557848 | 0.91 | RAB9A (0.42) | NPY5RCYP2D6RAB9ANPC1MAPT | |
| SCHEMBL17089615 | 0.91 | CYP2D6 (0.43) | NPY5RCYP2D6RAB9ANPC1MAPT | |
| SCHEMBL19362724 | 0.89 | CYP2D6 (0.48) | NPY5RCYP2D6RAB9ANPC1MAPT | |
| SCHEMBL9920888 | 0.84 | NPC1 (0.43) | CYP2D6RAB9ANPC1MAPTMEN1 | |
| SCHEMBL19361371 | 0.84 | RAB9A (0.52) | NPY5RCYP2D6RAB9ANPC1MAPT | |
| SCHEMBL19041677 | 0.83 | CYP2D6 (0.39) | CYP2D6RAB9ANPC1MAPTMEN1 | |
| SCHEMBL18162905 | 0.83 | CYP2D6 (0.52) | CYP2D6RAB9ANPC1MAPTMEN1 | |
| SCHEMBL9921100 | 0.83 | CYP2D6 (0.39) | CYP2D6RAB9ANPC1MAPTMEN1 | |
| SCHEMBL19362745 | 0.82 | CYP2D6 (0.46) | NPY5RCYP2D6RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580388-B2 | Pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |