Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3200799 | 0.96 | GPR52 (0.38) | GPR52TRPM8KDM4ENPC1MAPT | |
| SCHEMBL1851614 | 0.95 | GPR52 (0.38) | GPR52TRPM8KDM4ENPC1MAPT | |
| SCHEMBL1851317 | 0.89 | GPR52 (0.43) | GPR52TRPM8NPC1MAPTRAB9A | |
| SCHEMBL1859911 | 0.87 | GPR52 (0.46) | GPR52NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1852550 | 0.85 | GPR52 (0.46) | GPR52TRPM8NPC1MAPTRAB9A | |
| SCHEMBL1854460 | 0.84 | NPC1 (0.36) | GPR52TRPM8KDM4ENPC1MAPT | |
| SCHEMBL1850410 | 0.84 | GPR52 (0.47) | GPR52TRPM8NPC1MAPTRAB9A | |
| SCHEMBL1850115 | 0.82 | GPR52 (0.44) | GPR52NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1849690 | 0.81 | GPR52 (0.49) | GPR52TRPM8KDM4ENPC1MAPT | |
| SCHEMBL1851411 | 0.80 | NPC1 (0.37) | GPR52KDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |