Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MARK1 | Q9P0L2 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18558240 | 0.91 | RAB9A (0.52) | RAB9ACSNK2A2CSNK2A1GAKPDGFRB | |
| SCHEMBL18557603 | 0.91 | RAB9A (0.52) | RAB9ACSNK2A2CSNK2A1GAKPDGFRB | |
| SCHEMBL18558659 | 0.89 | RAB9A (0.45) | RAB9ACSNK2A2CSNK2A1GAKPDGFRB | |
| SCHEMBL18557814 | 0.87 | RAB9A (0.48) | RAB9ATNIKCSNK2A2CSNK2A1GAK | |
| SCHEMBL18558194 | 0.86 | RAB9A (0.47) | RAB9ATNIKCSNK2A2CSNK2A1GAK | |
| SCHEMBL18558632 | 0.86 | RAB9A (0.47) | RAB9ACSNK2A2CSNK2A1GAKPDGFRB | |
| SCHEMBL18558500 | 0.85 | RAB9A (0.45) | RAB9ACSNK2A2CSNK2A1GAKPDGFRB | |
| SCHEMBL18558663 | 0.84 | RAB9A (0.45) | RAB9ACDK2TNIKCSNK2A2CSNK2A1 | |
| SCHEMBL18558181 | 0.84 | RAB9A (0.45) | RAB9ACSNK2A2CSNK2A1GAKPDGFRB | |
| SCHEMBL18558517 | 0.84 | RAB9A (0.45) | RAB9ATNIKCSNK2A2CSNK2A1GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580388-B2 | Pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |