Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | HINT1 | P49773 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15678113 | 1.00 | ADORA3 (0.54) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL22266777 | 0.90 | ADORA3 (0.50) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL18605977 | 0.85 | ADORA3 (0.49) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL25758007 | 0.84 | ADORA3 (0.52) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL5995487 | 0.84 | ADORA3 (0.52) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL15677960 | 0.83 | POLG (0.51) | STING1PDE3BPDE3ANT5EPNP | |
| SCHEMBL24703672 | 0.82 | ADORA3 (0.54) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL15677988 | 0.82 | ADORA3 (0.54) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL3033632 | 0.82 | ADORA3 (0.54) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL14946338 | 0.82 | ADORA3 (0.54) | ADORA3STING1PDE3BPDE3AHINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580708-B2 | Multimeric oligonucleotides compounds | RANA THERAPEUTICS, INC. (US) | 2017-02-28 | — | — | US | disclosed |