Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18560362 | 0.64 | — | — | |
| SCHEMBL1775035 | 0.64 | — | — | |
| SCHEMBL14998051 | 0.60 | — | — | |
| SCHEMBL11197304 | 0.56 | — | — | |
| SCHEMBL8627083 | 0.56 | — | — | |
| SCHEMBL18560366 | 0.55 | TSHR (0.47) | MEN1TSHRKMT2A | |
| SCHEMBL11565768 | 0.49 | — | — | |
| SCHEMBL14998050 | 0.49 | — | — | |
| SCHEMBL2353726 | 0.48 | — | — | |
| SCHEMBL22207480 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953932-B1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AS AGGRECANASE INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS | MERCK PATENT GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |