SCHEMBL8627083

SCHEMBL8627083

CC1=NC(C)(C)C(=O)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7216154 0.72
SCHEMBL19790041 0.70
SCHEMBL6698827 0.70 TP53 (0.31)
SCHEMBL7752813 0.70 TP53 (0.31)
SCHEMBL22453298 0.69
SCHEMBL13196247 0.69
SCHEMBL11197304 0.68
SCHEMBL3384398 0.68 ALDH1A1 (0.46)
SCHEMBL7662936 0.68 MMP2 (0.37)
SCHEMBL6702374 0.68 ALOX15 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807778-B2 Influence of partial side chain hydrolysis on the growth and morphology of reactive polymer multilayers fabricated using azlactone-functionalized polymers WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-11-07 US disclosed
US-20230264171-A1 CHROMATOGRAPHY RESIN HAVING AN ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE LIGAND BIO-RAD LABORATORIES, INC. 2023-08-24 US disclosed
US-11666888-B2 Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand BIO-RAD LABORATORIES, INC. (US) 2023-06-06 US disclosed
US-20180022864-A1 HYDROCARBON POLYMERS HAVING TWO AZLACTONE END GROUPS BOSTIK SA (FR) 2018-01-25 US disclosed
EP-3272783-A1 HYDROCARBON POLYMERS WITH TWO AZLACTONE END GROUPS BOSTIK SA (FR) 2018-01-24 EP disclosed
US-9783571-B2 Isolation of cysteine containing peptides MARTIN WARHAM LANCE (US) 2017-10-10 US disclosed
US-20170022371-A1 Slippery Anti-Fouling Surfaces Fabricated from Reactive Polymer Multilayers WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-01-26 US disclosed
US-20170022372-A1 Synthetic Surfaces with Robust and Tunable Underwater Superoleophobicity WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-01-26 US disclosed
US-20150158905-A1 Isolation of Cysteine Containing Peptides MARTIN WARHAM LANCE (US) 2015-06-11 US disclosed
US-20130231260-A1 POLYMER SCAFFOLDS FOR ASSAY APPLICATIONS NVS Technologies, Inc. (US) 2013-09-05 US disclosed
WO-2013123409-A1 POLYMER SCAFFOLDS FOR ASSAY APPLICATIONS NVS Technologies, Inc. (US) 2013-08-22 WO disclosed
US-20110076466-A1 TONER COMPOSITION FOR ELECTROSTATIC PHOTOGRAPHY, DEVELOPER FOR ELECTROSTATIC PHOTOGRAPHY, METHOD OF FORMING ELECTROSTATIC PHOTOGRAPHIC IMAGE, AND ELECTROSTATIC PHOTOGRAPHIC IMAGE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-7662936-B2 detect, screen, and quantitate biological samples after administration of antibody conjugates, antibody-drug conjugates, antibodies, and fragments and metabolites thereof, by affinity separation, chromatography, and mass spectrometry; monomethyl auristatin drug and a thio-ether linkage GENENTECH, INC. (US) 2010-02-16 US disclosed
EP-0480568-B1 Post-processing stabilization of photothermographic emulsions MINNESOTA MINING & MFG (US) 1998-06-10 EP disclosed
US-5175081-A Post-processsing stabilization of photothermographic emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-12-29 US disclosed
EP-0480568-A2 Post-processing stabilization of photothermographic emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-15 EP disclosed