Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.56 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12993988 | 1.00 | EPHX1 (0.56) | EPHX1CASP2FAAHZDHHC20ZDHHC2 | |
| SCHEMBL18621827 | 1.00 | EPHX1 (0.56) | EPHX1CASP2FAAHZDHHC20ZDHHC2 | |
| SCHEMBL4555309 | 0.97 | — | — | |
| Bicarbonate SCHEMBL29287941 | 0.91 | EPHX1 (0.59) | EPHX1CASP2FAAHZDHHC20ZDHHC2 | |
| SCHEMBL4075630 | 0.90 | — | — | |
| SCHEMBL20542909 | 0.84 | CASP2 (0.67) | EPHX1CASP2FAAHNAAA | |
| Hydrochloric Acid SCHEMBL20542798 | 0.83 | CASP2 (0.65) | EPHX1CASP2FAAHNAAA | |
| SCHEMBL18751932 | 0.82 | EPHX1 (0.48) | EPHX1CASP2FAAHZDHHC20ZDHHC2 | |
| SCHEMBL18751935 | 0.82 | EPHX1 (0.48) | EPHX1CASP2FAAHZDHHC20ZDHHC2 | |
| SCHEMBL18751934 | 0.82 | EPHX1 (0.48) | EPHX1CASP2FAAHZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2938596-B1 | METHODS FOR PURIFICATION OF SERINE PROTEASES | PORTOLA PHARM INC (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-2416804-B1 | AMATOXIN-ARMED THERAPEUTIC CELL SURFACE BINDING COMPONENTS DESIGNED FOR TUMOUR THERAPY | FAULSTICH HEINZ DR (DE) | 2017-03-01 | — | — | EP | disclosed |