SCHEMBL1856299

SCHEMBL1856299

CCCCOP(OCc1ccccc1)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.45
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
AR P10275 1/20 0.41
HPGD P15428 1/20 0.38
CETP P11597 3/20 0.37
CHRNA7 P36544 2/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
MGLL Q99685 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445915 0.90 LTA4H (0.53) LTA4HALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL18544242 0.89 TSHR (0.47) LTA4HALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL430999 0.87 LTA4H (0.53) LTA4HALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL991869 0.85 LTA4H (0.53) LTA4HALDH1A1CYP3A4TSHRMAPK1
SCHEMBL29033057 0.85 LTA4H (0.52) LTA4HALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL11743736 0.85 TSHR (0.46) ALDH1A1L3MBTL1TSHR
SCHEMBL133337 0.83 LTA4H (0.51) LTA4HALDH1A1CYP3A4TSHRMAPK1
SCHEMBL1925999 0.83 LTA4H (0.51) LTA4HALDH1A1CYP3A4TSHRMAPK1
SCHEMBL465411 0.83 LTA4H (0.51) LTA4HALDH1A1CYP3A4TSHRMAPK1
SCHEMBL9446578 0.83 LTA4H (0.51) LTA4HALDH1A1CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2141197-B1 Polypropylene composition with improved properties BOREALIS AG (AT) 2011-05-25 EP claimed
EP-2141197-A1 Polypropylene composition with improved properties Borealis AG (AT) 2010-01-06 EP claimed
EP-3391386-B1 CABLE COMPRISING A FOAMED LAYER COMPRISING A POLYOLEFIN POLYMER AND A BLOWING AGENT BOREALIS AG (AT) 2019-09-25 EP disclosed
EP-3234008-B1 SUPERIOR STRESS WHITENING PERFORMANCE FOR BATTERY CASES ABU DHABI POLYMERS CO LTD BOROUGE LLC (AE) 2019-02-20 EP disclosed
EP-3391386-A1 CABLE COMPRISING A FOAMED LAYER COMPRISING A POLYOLEFIN POLYMER AND A BLOWING AGENT Borealis AG (AT) 2018-10-24 EP disclosed
US-20180301238-A1 CABLE COMPRISING A FOAMED LAYER COMPRISING A POLYOLEFIN POLYMER AND A BLOWING AGENT BOREALIS AG (AT) 2018-10-18 US disclosed
US-10011708-B2 Superior stress whitening performance for battery cases ABU DHABI POLYMERS CO. LTD (BOROUGE) LLC. (AE) 2018-07-03 US disclosed
US-20170313867-A1 SUPERIOR STRESS WHITENING PERFORMANCE FOR BATTERY CASES ABU DHABI POLYMERS CO. LTD (BOROUGE) LLC. (AE) 2017-11-02 US disclosed
WO-2017102341-A1 CABLE COMPRISING A FOAMED LAYER COMPRISING A POLYOLEFIN POLYMER AND A BLOWING AGENT BOREALIS AG (AT) 2017-06-22 WO disclosed
EP-3182419-A1 CABLE COMPRISING A FOAMED LAYER COMPRISING A POLYOLEFIN POLYMER AND A BLOWING AGENT Borealis AG (AT) 2017-06-21 EP disclosed
EP-2141197-B1 Polypropylene composition with improved properties BOREALIS AG (AT) 2011-05-25 EP disclosed
EP-2141197-A1 Polypropylene composition with improved properties Borealis AG (AT) 2010-01-06 EP disclosed