Sugi Predict

Sugi Predict / Compounds / SCHEMBL18564347

SCHEMBL18564347

SCHEMBL18564347

c1cc(-c2cc(-c3ccc(-n4c5ccccc5c5ccc6c7ccccc7sc6c54)cc3)nc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7sc6c54)c3)n2)cc(-n2c3ccccc3c3ccc4c5ccccc5sc4c32)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.34
▸ MEN1 O00255 4/20 0.34
▸ KMT2A Q03164 4/20 0.34
▸ KDM4E B2RXH2 3/20 0.34
▸ ALDH1A1 P00352 3/20 0.34
▸ HPGD P15428 3/20 0.34
▸ LMNA P02545 2/20 0.34
▸ ALOX5 P09917 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ ATM Q13315 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ NTSR1 P30989 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18564446 0.98 MAPT (0.34) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL9883288 0.95 MAPT (0.36) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL10014575 0.94 MEN1 (0.36) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL18564340 0.93 ALOX5 (0.34) MAPTMEN1KMT2AKDM4ELMNA
SCHEMBL18564437 0.93 ALOX5 (0.34) MAPTMEN1KMT2AKDM4ELMNA
SCHEMBL10014571 0.92 KMT2A (0.38) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL10014572 0.92 KMT2A (0.38) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL18564418 0.90 MAPT (0.36) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15625606 0.89 MEN1 (0.34) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL19129735 0.89 MAPT (0.33) MAPTMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 MAPT 1057/4885MEN1 1686/4885KMT2A 461/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 MAPT 1057/4885MEN1 1686/4885KMT2A 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.