SCHEMBL1856435

SCHEMBL1856435

CCO[Si](C)(C)COCC1CO1.CCO[Si](C)(COCC1CO1)OCC

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 4/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229581 0.93 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL4273637 0.93 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL28379589 0.80 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL9181404 0.79 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL188031 0.78 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5267684 0.78 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5271675 0.78 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL9181847 0.76 SMN1; SMN2 (0.65) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL10259489 0.75 TSHR (0.48) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL23521486 0.75 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904587-B8 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING (ALPHA)-SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2011-05-25 EP disclosed
EP-1904587-B1 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2010-11-03 EP disclosed
EP-1904587-A2 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCITON THEREOF Eckart GmbH (DE) 2008-04-02 EP disclosed
WO-2007098887-A2 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING α-SILANES AND METHOD FOR THE PRODUCITON THEREOF ECKART GMBH (DE) 2007-09-07 WO disclosed