SCHEMBL10259489

SCHEMBL10259489

C[Si](C)(COCC1CO1)O[Si](C)(C)COCC1CO1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 8/20 0.44
TDP1 Q9NUW8 2/20 0.44
GLA P06280 1/20 0.33
TP53 P04637 4/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
HIF1A Q16665 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
CYP3A4 P08684 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16744084 0.91 TSHR (0.45) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL1868365 0.84 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL12402259 0.82 ALDH1A1 (0.35) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL12928030 0.81 TSHR (0.52) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL4273637 0.81 SMN1; SMN2 (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL5266266 0.76 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL5266721 0.76 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL188286 0.76 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL230991 0.76 TSHR (0.47) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1
SCHEMBL16977255 0.75 TSHR (0.63) TSHRMAPK1SMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8349944-B2 Polymer dispersion in a reactive organic medium, preparation method and uses SAINT-GOBAIN ADFORS (FR) 2013-01-08 US disclosed
US-8212471-B2 Light emitting device and electronic equipment provided with the light emitting device SEIKO EPSON CORPORATION (JP) 2012-07-03 US disclosed
US-7910226-B2 Porous semiconductor layer formation material SEIKO EPSON CORPORATION (JP) 2011-03-22 US disclosed
US-7829639-B2 photopolymerizable bis(glycidyl-substituted-diphenylamino) compounds; polyepoxides; organic light emitting; electroluminescent; thin film transistor; switch; charge transfer; high reliability; solubility SEIKO EPSON CORPORATION (JP) 2010-11-09 US disclosed
US-20090214864-A1 POLYMER DISPERSION IN A REACTIVE ORGANIC MEDIUM, PREPARATION METHOD AND USES SAINT-GOBAIN VETROTEX FRANCE S.A. (FR) 2009-08-27 US disclosed
US-20090140635-A1 Porous semiconductor layer formation material SEIKO EPSON CORPORATION (JP) 2009-06-04 US disclosed
US-20090102359-A1 Light emitting device and electronic equipment provided with the light emitting device SEIKO EPSON CORPORATION (JP) 2009-04-23 US disclosed
US-20070286997-A1 Material Composition for Conductive Layers in Electronic Devices SEIKO EPSON CORPORATION (JP) 2007-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070286997-A1 Material Composition for Conductive Layers in Electronic Devices C1S, KCNH3, SLC9A2 TSHR 4212/4885MAPK1 556/4885SMN1; SMN2 2154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.