Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 17/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3200888 | 0.94 | GPR52 (0.68) | GPR52S1PR4S1PR5MAOB | |
| SCHEMBL1852707 | 0.86 | GPR52 (0.56) | GPR52S1PR4S1PR5 | |
| SCHEMBL1852567 | 0.85 | GPR52 (0.78) | GPR52S1PR4S1PR5 | |
| SCHEMBL1853172 | 0.85 | GPR52 (0.67) | GPR52S1PR4S1PR5 | |
| SCHEMBL1850787 | 0.83 | GPR52 (0.66) | GPR52S1PR4S1PR5 | |
| SCHEMBL1849577 | 0.83 | GPR52 (0.51) | GPR52 | |
| SCHEMBL1846879 | 0.83 | GPR52 (0.85) | GPR52S1PR4S1PR5 | |
| SCHEMBL1853546 | 0.82 | GPR52 (0.65) | GPR52S1PR4S1PR5 | |
| SCHEMBL3223178 | 0.82 | GPR52 (0.60) | GPR52S1PR4S1PR5MAOB | |
| SCHEMBL1854179 | 0.81 | GPR52 (0.62) | GPR52S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |