SCHEMBL18565005

SCHEMBL18565005

CN(c1ccccc1)c1ccc(-c2ccc(-c3ccc4c5c6ccccc6ccc5n(-c5ccc6ccccc6c5)c4c3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 4/20 0.34
MAPK9 P45984 3/20 0.34
HTR1D P28221 1/20 0.33
ALOX5 P09917 1/20 0.31
FAAH O00519 1/20 0.31
HPGD P15428 1/20 0.31
ITK Q08881 1/20 0.30
OPRD1 P41143 1/20 0.30
MAPK8 P45983 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565000 1.00 MAPK10 (0.34) MAPK10MAPK9HTR1DALOX5FAAH
SCHEMBL18564785 0.93 MAOB (0.33) ALOX5FAAHITK
SCHEMBL18564835 0.93 MAOB (0.33) ALOX5FAAHITK
SCHEMBL18565025 0.92 MAPK9 (0.32) MAPK10MAPK9HTR1DALOX5FAAH
SCHEMBL18566259 0.92 MAPK9 (0.32) MAPK10MAPK9HTR1DALOX5FAAH
SCHEMBL18564659 0.92 SIRT2 (0.34) HTR1DALOX5FAAHHPGDITK
SCHEMBL18564656 0.92 SIRT2 (0.34) HTR1DALOX5FAAHHPGDITK
SCHEMBL18564999 0.92 ITK (0.36) MAPK10MAPK9ALOX5HPGDITK
SCHEMBL18564899 0.91 OPRD1 (0.34) FAAHITKOPRD1ALDH1A1GAA
SCHEMBL18564910 0.91 OPRD1 (0.34) FAAHITKOPRD1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 MAPK10 1564/4885MAPK9 436/4885HTR1D 2523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.