SCHEMBL18565006

SCHEMBL18565006

Cn1c2cc(-c3ccc(-c4ccc(N(c5ccccc5)c5ccc6ccccc6c5)cc4)cc3)ccc2c2cc3ccccc3cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
HTR1D P28221 1/20 0.40
MAOB P27338 1/20 0.38
LIMK1 P53667 1/20 0.36
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
PIN1 Q13526 1/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
LMNA P02545 2/20 0.33
FGFR1 P11362 1/20 0.33
PER2 O15055 1/20 0.32
CRY1 Q16526 1/20 0.32
CRY2 Q49AN0 1/20 0.32
TSPO P30536 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565008 1.00 RXRA (0.41) RXRARXRBHTR1DMAOBLIMK1
SCHEMBL18589855 0.95 HTR1D (0.39) RXRARXRBHTR1DMAOBLIMK1
SCHEMBL18564688 0.95 RXRA (0.45) RXRARXRBHTR1DMAOBLIMK1
SCHEMBL18564814 0.95 RXRA (0.45) RXRARXRBHTR1DMAOBLIMK1
SCHEMBL18564788 0.93 RXRA (0.44) RXRARXRBHTR1DMAOBLIMK1
SCHEMBL18564831 0.93 RXRA (0.44) RXRARXRBHTR1DMAOBLIMK1
SCHEMBL18565010 0.93 KDM4E (0.36) HTR1DNPC1RAB9AL3MBTL1LMNA
SCHEMBL18565026 0.92 HTR1D (0.37) RXRARXRBHTR1DMAOBNPC1
SCHEMBL18565030 0.92 HTR1D (0.37) RXRARXRBHTR1DMAOBNPC1
SCHEMBL18564894 0.92 RXRA (0.41) RXRARXRBHTR1DMAOBLIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 RXRA 4249/4885RXRB 4487/4885HTR1D 2523/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 RXRA 4249/4885RXRB 4487/4885HTR1D 2523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.