Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | GALR1 | P47211 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1851421 | 0.96 | GPR52 (0.53) | GPR52NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL1856035 | 0.87 | GPR52 (0.49) | GPR52NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL1848497 | 0.85 | HPGD (0.47) | GPR52NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL1851841 | 0.84 | GPR52 (0.48) | GPR52NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL1849212 | 0.83 | GPR52 (0.53) | GPR52SLC9A1 | |
| SCHEMBL1847924 | 0.83 | GPR52 (0.56) | GPR52NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL1850522 | 0.83 | GPR52 (0.70) | GPR52NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL3204287 | 0.83 | GPR52 (0.50) | GPR52NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL1851960 | 0.82 | GPR52 (0.55) | GPR52NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL3208929 | 0.80 | GPR52 (0.47) | GPR52NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |