Sugi Predict

Sugi Predict / Compounds / SCHEMBL18565247

SCHEMBL18565247

SCHEMBL18565247

c1ccc(N(c2cccc(-c3nc(-c4cccc(N(c5ccccc5)c5ccc6c7ccccc7n(-c7ccccc7)c6c5)c4)nc(-c4cccc(N(c5ccccc5)c5ccc6c7ccccc7n(-c7ccccc7)c6c5)c4)n3)c2)c2ccc3c4ccccc4n(-c4ccccc4)c3c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ KDM4E B2RXH2 2/20 0.45
▸ ATM Q13315 1/20 0.45
▸ KMT2A Q03164 2/20 0.34
▸ IL1R1 P14778 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ PTGER4 P35408 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ ABCG2 Q9UNQ0 1/20 0.33
▸ MAT2A P31153 4/20 0.32
▸ PRMT5 O14744 2/20 0.32
▸ CYP1A2 P05177 2/20 0.32
▸ MGAM O43451 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ SI P14410 1/20 0.32
▸ MGAM2 Q2M2H8 1/20 0.32
▸ PDE5A O76074 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18565328 0.98 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18565352 0.95 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18565229 0.95 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18565244 0.94 KDM4E (0.42) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18565248 0.94 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18565236 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18565242 0.92 KDM4E (0.47) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL23308271 0.92 KDM4E (0.42) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL23308272 0.92 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18565358 0.91 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-05-14 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290815-B2 Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device EED, BMI1, CD99 L3MBTL1 1263/4885KDM4E 225/4885ATM 3092/4885
US-20170062733-A1 COMPOSITION, COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, INK COMPOSITION, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE EED, BMI1, CD99 L3MBTL1 1263/4885KDM4E 225/4885ATM 3092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.