Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18567785 | 0.91 | — | — | |
| SCHEMBL6876647 | 0.83 | ELANE (0.39) | ELANE | |
| SCHEMBL18400763 | 0.82 | NR1I2 (0.42) | — | |
| SCHEMBL19204604 | 0.82 | CTSB (0.43) | ELANE | |
| SCHEMBL20610259 | 0.82 | NR1I2 (0.42) | — | |
| SCHEMBL19250965 | 0.82 | NR1I2 (0.42) | — | |
| SCHEMBL18533097 | 0.82 | NR1I2 (0.42) | — | |
| SCHEMBL18430683 | 0.82 | CTSB (0.43) | ELANE | |
| SCHEMBL20610257 | 0.81 | CYP3A4 (0.37) | — | |
| SCHEMBL18400766 | 0.81 | NR1I2 (0.41) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459525-B1 | ENANTIO- AND STEREO-SPECIFIC SYNTHESES OF -AMINO- - HYDROXY AMIDES | MERCK SHARP & DOHME (US) | 2017-03-01 | — | — | EP | disclosed |