SCHEMBL1856780

SCHEMBL1856780

[CH2]C(C)C1CCC2(C)OC2C1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.36
FTH1 P02794 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 1/20 0.33
PDE4D Q08499 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21473189 0.84 CYP3A4 (0.36) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL21473331 0.84 CYP3A4 (0.36) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL14776371 0.84 CYP3A4 (0.36) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL14849904 0.84 CYP3A4 (0.36) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL21473187 0.84 CYP3A4 (0.36) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL18553077 0.84 CYP3A4 (0.36) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL2852967 0.84 CYP3A4 (0.36) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL24052372 0.78 PDE4D (0.33) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL13935542 0.78 CYP3A4 (0.34) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1
SCHEMBL10261799 0.78 PDE4D (0.33) CYP3A4FTH1CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140060324-A1 METHOD OF PREPARING GAS SELECTIVE MEMBRANE USING EPOXY-FUNCTIONAL SILOXANES DOW CORNING CORPORATION (US) 2014-03-06 US claimed
US-7771794-B2 Active energy ray-curable, organopolysiloxane resin composition, light-transmitting component, and method for manufacturing the light-transmitting component DOW CORNING CORPORATION (US) 2010-08-10 US claimed
EP-0476925-B1 UV light-curable organopolysiloxane composition SHINETSU CHEMICAL CO (JP) 1996-12-11 EP claimed
US-5364888-A Polyoxyalkylene glycol provides improved miscibility with onium salt initiator SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-11-15 US claimed
CN-1023230-C Oxidation resistant compositions for use with rare earth magnets GOODRICH CO B F (US) 1993-12-22 CN claimed
EP-0476925-A2 UV light-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-03-25 EP claimed
EP-0179355-B1 NOVEL TERPENE DERIVED FUNCTIONAL SILANES PCR GROUP, INC. (US) 1991-01-16 EP claimed
CN-1039832-A The antioxidizing composition that is used for rare-earth magnet GOODRICH CO B F (US) 1990-02-21 CN claimed
EP-0179355-A2 Novel terpene derived functional silanes PCR GROUP, INC. (US) 1986-04-30 EP claimed
WO-2024145273-A2 N-MYRISTOYLTRANSFERASE INHIBITORS AND METHODS OF USE SEATTLE CHILDREN'S HOSPITAL (D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE) (US) 2024-07-04 WO disclosed
EP-4392430-A1 MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS Yale University (US) 2024-07-03 EP disclosed
US-20240181438-A1 UNSYMMETRICAL N-HETEROCYCLIC CARBENE CATALYSTS AND METHODS USING SAME RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-06-06 US disclosed
US-20240165597-A1 STERICALLY HINDERED N-ALIPHATIC N-HETEROCYCLIC CARBENE CATALYSTS AND METHODS USING SAME RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-05-23 US disclosed
WO-2024097160-A1 TRANSITION METAL COMPLEXES FOR MRI APPLICATIONS AND METHODS OF USE YALE UNIVERSITY (US) 2024-05-10 WO disclosed
CN-1023230-C Oxidation resistant compositions for use with rare earth magnets GOODRICH CO B F (US) 1993-12-22 CN disclosed
US-5190988-A Ultraviolet-curable organopolysiloxane composition containing a benzoinsulphonate initiator and metal catalyst SHIN-ETSU CHEMICAL COMPANY, LIMITED (JP) 1993-03-02 US disclosed
EP-0523527-A2 Curable silicone-based release agent, separator having cured film formed from the same, and pressure-sensitive tape having cured film formed from the same NITTO DENKO CORPORATION (JP) 1993-01-20 EP disclosed
EP-0476925-A2 UV light-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-03-25 EP disclosed
EP-0179355-B1 NOVEL TERPENE DERIVED FUNCTIONAL SILANES PCR GROUP, INC. (US) 1991-01-16 EP disclosed
CN-1039832-A The antioxidizing composition that is used for rare-earth magnet GOODRICH CO B F (US) 1990-02-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240181438-A1 UNSYMMETRICAL N-HETEROCYCLIC CARBENE CATALYSTS AND METHODS USING SAME NDC1, NUDC, NSFL1C CYP3A4 408/4885FTH1 1362/4885CYP2C9 2032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.