Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FTH1 | P02794 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852967 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL30781980 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL30781958 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL14849904 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL18553077 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL21473189 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL14776371 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL29534511 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL21473187 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL1856780 | 0.84 | CYP3A4 (0.36) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242569-A1 | PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE | 2023-08-03 | — | — | US | disclosed |
| US-20190322694-A1 | NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE | 2019-10-24 | — | — | US | disclosed |
| WO-2019200273-A1 | NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242569-A1 | PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | PPIP5K2, INPP5B, PTMS | CYP3A4 321/4885ALDH1A1 4574/4885FTH1 1397/4885 |
| US-20190322694-A1 | NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | PPIP5K2, INPP5B, PTMS | CYP3A4 318/4885ALDH1A1 4621/4885FTH1 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.