SCHEMBL18567969

SCHEMBL18567969

CCCC[C@@H](OC)[C@H](O)c1c(C)cccc1Cl

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYSLTR2 Q9NS75 1/20 0.30
CYSLTR1 Q9Y271 1/20 0.30
PTGES O14684 1/20 0.30
ALOX5 P09917 1/20 0.30
PPARG P37231 1/20 0.30
PPARA Q07869 1/20 0.30
CTSK P43235 1/20 0.30
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19254451 1.00 MEN1 (0.36) MEN1KMT2AKDM4EHSD17B10CYSLTR2
SCHEMBL23347628 1.00 MEN1 (0.36) MEN1KMT2AKDM4EHSD17B10CYSLTR2
SCHEMBL16064847 1.00 MEN1 (0.36) MEN1KMT2AKDM4EHSD17B10CYSLTR2
SCHEMBL19254217 0.91 MEN1 (0.38) MEN1KMT2AHSD17B10ALOX5CTSK
SCHEMBL18567950 0.85 KDM4E (0.34) MEN1KMT2AKDM4EHSD17B10TAS1R3
SCHEMBL16070561 0.85 KDM4E (0.34) MEN1KMT2AKDM4EHSD17B10TAS1R3
SCHEMBL16064835 0.82 MEN1 (0.36) MEN1KMT2AKDM4ECYSLTR2CYSLTR1
SCHEMBL16070864 0.80 MEN1 (0.38) MEN1KMT2AHSD17B10CTSKTAS1R3
SCHEMBL19415516 0.78 CASP1 (0.40) MEN1KMT2AKDM4EPPARGCTSK
SCHEMBL23347597 0.76 MAPK11 (0.32) MEN1KMT2AKDM4ECYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2527314-B1 Process for preparation of phenyl carbamate derivatives BIO-PHARM SOLUTIONS CO LTD (KR) 2017-10-04 EP disclosed
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed
EP-2797880-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY BIO-PHARM SOLUTIONS CO LTD (KR) 2017-03-01 EP disclosed