Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2717735 | 0.87 | MEN1 (0.34) | BCHEMEN1KMT2A | |
| SCHEMBL2719573 | 0.87 | MEN1 (0.34) | BCHEMEN1KMT2A | |
| SCHEMBL12306538 | 0.87 | MEN1 (0.34) | BCHEMEN1KMT2A | |
| SCHEMBL13792726 | 0.85 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL2719570 | 0.80 | ALDH1A1 (0.33) | BCHEMEN1KMT2A | |
| SCHEMBL12306645 | 0.79 | HTT (0.31) | — | |
| SCHEMBL12306649 | 0.79 | HTT (0.31) | — | |
| SCHEMBL12306521 | 0.79 | — | — | |
| SCHEMBL1665722 | 0.78 | GSTP1 (0.32) | — | |
| SCHEMBL18568728 | 0.77 | ALDH1A1 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2850092-B1 | TRICYCLIC NUCLEIC ACID ANALOGS | IONIS PHARMACEUTICALS INC (US) | 2017-03-01 | — | — | EP | disclosed |