Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654298 | 0.82 | PFKFB3 (0.46) | PRF1 | |
| SCHEMBL18569072 | 0.81 | MAPK1 (0.31) | — | |
| SCHEMBL18568972 | 0.77 | MAPK1 (0.32) | — | |
| SCHEMBL18568867 | 0.73 | MAPK1 (0.31) | — | |
| SCHEMBL18568992 | 0.72 | MAPK1 (0.31) | — | |
| SCHEMBL18568656 | 0.71 | MAPK1 (0.31) | — | |
| SCHEMBL18568996 | 0.70 | — | — | |
| SCHEMBL18569005 | 0.69 | — | — | |
| SCHEMBL3027155 | 0.66 | BRD4 (0.41) | — | |
| SCHEMBL1653333 | 0.65 | HTT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-03-01 | — | — | EP | disclosed |