Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18569084 | 0.84 | GAA (0.33) | HSD17B10ALDH1A1MAPT | |
| SCHEMBL18569072 | 0.83 | MAPK1 (0.31) | MAPK1HSD17B10ALDH1A1MAPTHPGD | |
| SCHEMBL18569097 | 0.82 | MAPK1 (0.32) | MAPK1HSD17B10 | |
| SCHEMBL18569086 | 0.82 | ALDH1A1 (0.30) | ALDH1A1MAPT | |
| SCHEMBL18568894 | 0.81 | — | — | |
| SCHEMBL18568624 | 0.80 | MMP13 (0.36) | — | |
| SCHEMBL18568867 | 0.79 | MAPK1 (0.31) | MAPK1HSD17B10 | |
| SCHEMBL18568614 | 0.79 | METAP1 (0.34) | ALDH1A1 | |
| SCHEMBL18568992 | 0.78 | MAPK1 (0.31) | MAPK1HSD17B10 | |
| SCHEMBL18568656 | 0.78 | MAPK1 (0.31) | MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-03-01 | — | — | EP | disclosed |