Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568684 | 0.76 | POLB (0.59) | MAPTRXFP1POLBHPGDMEN1 | |
| SCHEMBL9995861 | 0.76 | POLB (0.59) | MAPTRXFP1POLBHPGDMEN1 | |
| SCHEMBL23417495 | 0.68 | CYP2C19 (0.68) | MAPTPOLBHPGDMEN1KMT2A | |
| SCHEMBL11960890 | 0.66 | MAPK10 (0.63) | MAPTRXFP1POLBHPGDMEN1 | |
| SCHEMBL15679868 | 0.65 | POLB (0.64) | MAPTPOLBHPGDMEN1KMT2A | |
| SCHEMBL4034002 | 0.65 | CYP2C19 (0.60) | POLBMEN1KMT2AKDM4ELMNA | |
| SCHEMBL2362584 | 0.64 | POLB (0.61) | MAPTRXFP1POLBHPGDMEN1 | |
| SCHEMBL2363650 | 0.64 | VCP (0.46) | MAPTRXFP1POLBHPGDMEN1 | |
| SCHEMBL7272444 | 0.64 | TAAR1 (0.64) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL2354757 | 0.64 | KMT2A (0.58) | MAPTRXFP1POLBHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135672-A1 | COMPOSITIONS AND METHODS FOR TREATING ALCOHOL USE DISORDERS, PAIN AND OTHER DISEASES | VM Discovery, Inc. (US) | 2017-03-01 | — | — | EP | disclosed |