Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18568722 | 0.91 | — | — | |
| SCHEMBL18568732 | 0.83 | CDK1 (0.41) | MAPTSMN1; SMN2 | |
| SCHEMBL18568988 | 0.82 | ALDH1A1 (0.36) | MAPTSMN1; SMN2 | |
| SCHEMBL18568892 | 0.80 | SMYD3 (0.32) | — | |
| SCHEMBL18569001 | 0.80 | HRH4 (0.34) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL18568985 | 0.80 | CDK1 (0.44) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL1654083 | 0.79 | KMT2A (0.38) | TP53MAPT | |
| SCHEMBL18568897 | 0.78 | HRH4 (0.33) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL18568754 | 0.78 | — | — | |
| SCHEMBL18568978 | 0.77 | HRH4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308839-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICALS CO (JP) | 2017-03-01 | — | — | EP | disclosed |