Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13048826 | 0.90 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL13048774 | 0.88 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL18569340 | 0.80 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL13048022 | 0.80 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL17589862 | 0.79 | ALDH1A1 (0.41) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL17589957 | 0.79 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL13048343 | 0.78 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL13074954 | 0.78 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL13048841 | 0.76 | KDM4E (0.43) | CYP1A2CYP3A4CYP2C19LMNAKDM4E | |
| SCHEMBL16660143 | 0.76 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |