Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16526501 | 0.94 | SLC6A2 (0.38) | NOS2NOS3NOS1PRCPDPP7 | |
| SCHEMBL31351975 | 0.79 | PRCP (0.44) | NOS2NOS3NOS1PRCPDPP7 | |
| SCHEMBL27677511 | 0.78 | PRCP (0.46) | NOS2NOS3NOS1PRCPDPP7 | |
| SCHEMBL24620429 | 0.78 | — | — | |
| SCHEMBL3330660 | 0.77 | PRCP (0.45) | NOS2NOS3NOS1PRCPDPP7 | |
| SCHEMBL7306276 | 0.77 | NOS2 (0.39) | NOS2NOS3NOS1PRCPDPP7 | |
| SCHEMBL115996 | 0.77 | PRCP (0.45) | NOS2NOS3NOS1PRCPDPP7 | |
| SCHEMBL10829027 | 0.77 | PRCP (0.45) | NOS2NOS3NOS1PRCPDPP7 | |
| SCHEMBL133135 | 0.77 | PRCP (0.45) | NOS2NOS3NOS1PRCPDPP7 | |
| Hydrochloric Acid SCHEMBL1073479 | 0.76 | PRCP (0.44) | NOS2NOS3NOS1PRCPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016942-B1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES | DSM IP ASSETS BV (NL) | 2017-03-01 | — | — | EP | disclosed |