Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290713 | 0.85 | APP (0.38) | APPPIK3CGDYRK1ACYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL17629274 | 0.84 | APP (0.37) | APPPIK3CGDYRK1ACYP11B1CYP11B2 | |
| SCHEMBL18569269 | 0.80 | CYP11B1 (0.38) | PIK3CGDYRK1ACYP11B1CYP11B2PIM1 | |
| SCHEMBL289594 | 0.79 | ALOX15 (0.46) | APPPIK3CGDYRK1ACYP11B1CYP11B2 | |
| SCHEMBL13048201 | 0.77 | DYRK1A (0.40) | PIK3CGDYRK1APIM1CYP17A1 | |
| SCHEMBL18569019 | 0.76 | PIK3CG (0.35) | PIK3CGDYRK1A | |
| SCHEMBL13048209 | 0.75 | PIK3CG (0.37) | PIK3CGDYRK1APIM1HDAC6 | |
| SCHEMBL13048214 | 0.74 | DYRK1A (0.38) | PIK3CGDYRK1APIM1HDAC6 | |
| SCHEMBL17641052 | 0.74 | PIM1 (0.38) | APPPIK3CGDYRK1ACYP11B1CYP11B2 | |
| SCHEMBL25405384 | 0.73 | PIK3CG (0.44) | PIK3CGDYRK1APIM1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |