SCHEMBL18569641

SCHEMBL18569641

Nc1cc(NC(=O)c2ccc(-c3ccccc3)c(CN3CCOCC3)c2)ccc1O

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18569419 0.82 TRPV1 (0.73) TRPV1
SCHEMBL12992334 0.79 TRPV1 (0.84) TRPV1
SCHEMBL12992555 0.78 TRPV1 (1.00) TRPV1
SCHEMBL12991795 0.78 TRPV1 (0.56) TRPV1
SCHEMBL12992089 0.77 TRPV1 (1.00) TRPV1
SCHEMBL18569234 0.76 TRPV1 (0.72) TRPV1
SCHEMBL12992699 0.76 TRPV1 (0.63) TRPV1
SCHEMBL30865830 0.76 MOK (0.63) TRPV1
SCHEMBL12992331 0.75 TRPV1 (0.72) TRPV1
SCHEMBL12992385 0.75 TRPV1 (0.73) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1632477-B1 BENZAMIDE DERIVATIVE OR SALT THEREOF ASTELLAS PHARMA INC (JP) 2017-03-01 EP disclosed