Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 7/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865839 | 0.80 | MOK (0.47) | MOKTRPV1RAB9ACNR2ALDH1A1 | |
| SCHEMBL12991795 | 0.77 | TRPV1 (0.56) | TRPV1SMN1; SMN2ALDH1A1MAPTCYP3A4 | |
| SCHEMBL19475600 | 0.77 | MOK (1.00) | MOK | |
| SCHEMBL18569641 | 0.76 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL13681862 | 0.76 | CYP3A4 (0.56) | SMN1; SMN2NPC1RAB9ACNR2ALDH1A1 | |
| SCHEMBL12991473 | 0.76 | ALDH1A1 (0.58) | TRPV1SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL28792775 | 0.75 | CYP2C9 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL13038406 | 0.73 | CYP3A4 (0.53) | TRPV1ALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL12992555 | 0.73 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL28792758 | 0.72 | DRD2 (0.54) | TRPV1SMN1; SMN2ALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917402-A | Isoindolylamide compound, and pharmaceutical composition and application thereof | 暨南大学 | 2024-04-23 | — | — | CN | disclosed |