Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14329369 | 0.88 | HTR2B (0.36) | HTR2BCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL14826661 | 0.86 | LMNA (0.36) | PDE7AGAA | |
| SCHEMBL15919806 | 0.86 | LMNA (0.36) | PDE7AGAA | |
| SCHEMBL24418400 | 0.83 | HTR2A (0.42) | HTR2AHTR2CHTR2BPDE7A | |
| SCHEMBL8341378 | 0.78 | PARP2 (0.42) | HTR2AHTR2CHTR2BACHEPARP2 | |
| SCHEMBL25045333 | 0.77 | PDE7A (0.40) | HTR2AHTR2CHTR2BACHEPARP2 | |
| SCHEMBL25044728 | 0.76 | HTR2C (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL25043951 | 0.76 | MAPT (0.34) | SMN1; SMN2 | |
| SCHEMBL25043947 | 0.76 | PIK3C3 (0.33) | — | |
| SCHEMBL12309469 | 0.75 | KDM5A (0.42) | HTR2AHTR2CHTR2BCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004084-B1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma AG (DE) | 2017-03-01 | — | — | EP | disclosed |