Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157476 | 0.90 | RECQL (0.51) | RECQLAPOBEC3AAPOBEC3GTSHRTHRB | |
| SCHEMBL26723886 | 0.85 | RECQL (0.47) | RECQLAPOBEC3AAPOBEC3GTSHRTHRB | |
| SCHEMBL30157390 | 0.81 | SLC6A2 (0.42) | RECQLTSHRKMT2ACA12CA1 | |
| SCHEMBL30157878 | 0.80 | RECQL (0.41) | RECQLTSHRTP53KMT2ACA12 | |
| SCHEMBL6270407 | 0.76 | RECQL (1.00) | RECQLTSHRMAPTKMT2AMAPK1 | |
| SCHEMBL6271734 | 0.76 | RECQL (0.59) | RECQLAPOBEC3AAPOBEC3GTSHRTHRB | |
| SCHEMBL19998591 | 0.76 | POLB (0.57) | TSHRMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL435086 | 0.76 | POLB (0.57) | TSHRMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL20040955 | 0.75 | NR2E1 (0.42) | RECQLTSHRTP53MAPTKMT2A | |
| SCHEMBL12235705 | 0.73 | RXFP1 (0.52) | RECQLTSHRMAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390340-B1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2017-03-01 | — | — | EP | disclosed |