Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15542604 | 0.76 | NR2E1 (0.41) | NR2E1 | |
| SCHEMBL18570204 | 0.75 | RECQL (0.61) | RECQLSMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL30157878 | 0.73 | RECQL (0.41) | RECQLDPP4LMNAMEN1KMT2A | |
| SCHEMBL10445909 | 0.73 | DPP4 (0.39) | NR2E1RECQLDPP4MEN1KMT2A | |
| SCHEMBL2747819 | 0.72 | LMNA (0.46) | NR2E1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27508461 | 0.72 | ADRB1 (0.46) | NR2E1DPP4MEN1KMT2AUSP2 | |
| SCHEMBL30157390 | 0.72 | SLC6A2 (0.42) | RECQLMEN1KMT2APOLBCA12 | |
| SCHEMBL26723886 | 0.71 | RECQL (0.47) | RECQLGRM5KMT2ACA12CA1 | |
| SCHEMBL16904558 | 0.71 | NR2E1 (0.43) | NR2E1DPP4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5841909 | 0.70 | RECQL (0.62) | RECQLSMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | disclosed |